Week 12 NFL picks: Bills-Chiefs and all others

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Nov 22, 2015; Atlanta, GA, USA; Atlanta Falcons quarterback Matt Ryan (2) attempts a pass in the first quarter of their game against the Indianapolis Colts at the Georgia Dome. Mandatory Credit: Jason Getz-USA TODAY Sports

Minnesota Vikings at Atlanta Falcons (-1)

Atlanta (6-4) has to win this game. The Falcons have lost four of their last five games and are in real danger of falling out of the playoff picture. Minnesota (7-3) will also be fairly desperate, but it has more wiggle room and this will be a tough chore on the road.

Pick: Atlanta 27, Minnesota 20

St. Louis Rams at Cincinnati Bengals (-10)

Cincinnati (8-2) is coming home and it is not going to lose to Case Keenum. St. Louis (4-6) is a lousy team coming off two consecutive losses to the Bears and Ravens. This game should not be close.

Pick: Cincinnati 24, St. Louis 9

New Orleans Saints at Houston Texans (-3)

Houston (5-5) is very hard to figure. The defense has some pieces but the offense is absolutely useless beyond DeAndre Hopkins. New Orleans (4-6) is the exact opposite, with a great offense and no defense. Always take the defense.

Pick: Houston 30, New Orleans 26

Tampa Bay Buccaneers at Indianapolis Colts (-3)

Another odd game. Tampa Bay (5-5) just pounded the Eagles on the road with Jameis Winston throwing five touchdown passes. Meanwhile, Indianapolis (5-5) is undefeated with Matt Hasselbeck at the helm.

Pick: Indianapolis 19, Tampa Bay 17

Next: More form the early window...