Week 6: vs Buffalo Bills (3:25, CBS)
In arguably the most anticipated game of the year, the Buffalo Bills return to Arrowhead for the first time since the classic divisional round game last season which saw Kansas City come out on top 42-36 in overtime.
This will likely be the toughest game of the regular season for Kansas City as Josh Allen is the second-best quarterback in football (behind only Patrick Mahomes) and Buffalo should have one of the strongest defenses in the entire league.
This, unfortunately, could be a huge letdown for Kansas City like it was in the same spot last year. The Chiefs will likely be still adjusting on defense and the Bills are in a position to take advantage of that. Kansas City will lose their first home game of the season to one of their biggest rivals.
Result: Chiefs LOSE 34-27 and fall to 4-2.
Week 7: at San Francisco 49ers (3:25, FOX)
The Chiefs travel to Santa Clara for a regular season matchup for the first time since 2014. The Niners are coming off of an appearance in the NFC Championship in which they surrendered (another) 10-point lead and fell short of another Super Bowl trip. Oh, and this is also the first regular season matchup between Kansas City and San Francisco since Super Bowl LIV.
The 49ers are one of the boom or bust teams in the entire NFL. Every season since 2010, except for 2014, they have either lost 10+ games or made it to at least the NFC Title Game. They have the potential to be one of the most dangerous teams in football or could flame out similar to in 2020. Trey Lance will dictate how their season goes and if he struggles, they will in turn struggle to win games.
The Chiefs will go on the road and get a well-earned victory against the team they defeated in Super Bowl LIV.
Result: Chiefs WIN 24-17 and improve to 5-2.
Week 8: Bye Week
Week 9: vs Tennessee Titans (7:20, NBC)
Coming off their bye, the Kansas City Chiefs will face off against the Tennessee Titans, a team that has given them trouble ever since Andy Reid came to Kansas City (The Titans own a 5-2 record against the Chiefs since 2013). At the same time, the Chiefs are 10-3 off of bye weeks since Reid was hired so something has to give.
The Titans are a hard team to gauge. On one hand, they were the #1 seed in the AFC last season despite losing star running back Derrick Henry to an injury for much of the season. On the other hand, they never quite felt like a top team in the NFL and they proved that correct when they went one-and-done in the playoffs last year.
The Chiefs should win this game but it won’t be easy. The Titans always play the Chiefs tough and this game will not be fun for Kansas City fans.
Result: Chiefs WIN 23-20 and go to 6-2.